Biorepository of autopsy tissues

The Biorepository of autopsy tissues contains formalin-fixed tissues and histological specimens (paraffin blocks and slides) obtained from autopsy of 1004 individuals died in Ozersk in 19512016.

Breakdown of Mayak PA workers-donors of autopsy tissues due to plant.

Breakdown of Mayak PA workers and not exposed Ozersk residents by gender.

The RHTR stores specimens of formalin-fixed soft tissues from 815 registrants and bone tissues from 518 individuals. 981 cases are provided with paraffin blocks and slides.

Breakdown of the RHTR registrants due to type of tissues and organs (formalin-fixed soft tissues).

1a) Internal organs

The number of cases

1b) Cerebrum and other organs/tissues

Samples Cerebrum Thyroid gland Adrenal glands Reproductive organs Lymphoid tissue
The number of cases Hemisphere Cerebellum Testicles Prostate gland Ovary Uterus Spleen Lymph nodes

Breakdown of the RHTR registrants due to type of bone tissues and storage conditions.

2) Decalcified bones (stored in ethanol)

Samples
The number of cases

2b) Non-decalcified bones (stored in formalin)

Samples
The number of cases

Medical information.

In the RHTR database there are data about morbidity and causes of death for all registrants.
Malignant neoplasms of different sites (ICD-10, codes C00-C97) caused death of 552 from 1004 registrants, total 580 cancer cases.

Breakdown of the RHTR registrants due to site of malignant neoplasms.

  The number of cases
Respiratory system Lungs 266
Other 5
Digestive system Stomach 80
Pancreas 32
Intestines 42
Liver 39
Other 24
Hematopoietic /Lymphoid tissue Leukemia 36
Other 13
Reproductive organs Testicles 2
Prostate gland 31
Ovary 2
Uterus 8
Urinary system Kidneys 19
Bladder 8
Urinary organs   20
Skin   34
Mammary gland   14
Other   22

Data on malignant neoplasms (number of tumors and storage methods).

The number of cases Malignant neoplasm Primary neoplasm Metastases
Formalin-fixed tissues Paraffin blocks Slides To regional lymph nodes To other organs/tissues
Formalin-fixed tissues Paraffin blocks Slides Formalin-fixed tissues Paraffin blocks Slides
245 lungs 129 215 222 33 57 64 110 171 178
37 liver 34 36 35 4 4 6 17 19 19
36 intestines 28 29 31 7 6 6 20 23 24
73 stomach 44 63 39 10 15 19 42 54 54
30 pancreas 26 27 27 5 5 5 18 24 22
15 kidneys 10 12 13 3 3 5 6 6
27 prostata 25 25 25 6 8 8 13 15 15

Occupational diseases (caused by radiation) were registered for 323 registrants Mayak PA workers:

  Female Male F+M

All registrants are provided with medical-dosimetry characteristics.

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